These include endodermal sinus tumors, embryonal carcinoma , immature teratoma, choriocarcinoma and mixed germ cell tumors.
Stage I
Standard Treatment Removal of the affected tube and ovary is generally all that is required since these tumors rarely occur in both ovaries.
Postoperative chemotherapy including cisplatin , bleomycin and etoposide is given to all patients for four courses with the exception of Grade 1 (well-differentiated) immature teratomas.
Vincristine, actinomycin-D and Cytoxan may be used in women who develop progressive disease.
Investigational
• Other combinations of chemotherapy, including carboplatin and ifosfamide , are currently under investigation.
Stages II, III and IV
Standard Treatment Depending on the extent and location of disease, a hysterectomy , bilateral removal of the tubes and ovaries, and aggressive tumor debulking . If the opposite ovary and uterus are normal, they can be
